Guess I'm going to have to re-read Neuromancer soon. . .
I remember when I first heard about Cube. Like so many movies, the trailer was better than the feature. But It did prompt me to watch each of its sequels. (for a really good Canadian film check out Foolproof)
I haven't seen Splice yet. It really doesn't look like my thing.
At any rate, I think Natali is probably the right man for the job.